Titlebook: Neuroblastoma; Clinical and Surgica Sabine Sarnacki,Luca Pio Book 2020 Springer Nature Switzerland AG 2020 pediatric surgery.pediatric onco

安装

headlong

Radiologycations. The treatment planning for radiation therapy that is recommended for high-risk neuroblastoma (NB) is based on imaging data. Finally, long-term post treatment follow-up includes recurrent imaging which should be adjusted to the risk of local or distant relapse.

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Neonatal Neuroblastoma lessen exposure to surgical intervention and chemotherapy risk in this very fragile population. In this review, we discuss the epidemiology, clinical presentation, staging, biology, and treatment for neonates with neuroblastoma.

Goblet-Cells

Immunotherapytrategies, such as the infusion of monoclonal antibodies or of adoptive T cells redirected against the tumor. NBL tumor immunology and preclinical and clinical immunotherapy strategies are the object of the present chapter.

格子架

Biopsy of Neuroblastomaal and numerical chromosomal aberrations including 1p, 11q) play a vital role, in addition to the age and extent of disease. Therefore, the key role of adequate solid tumour biopsy in the diagnosis and prognostic decision-making of patients with neuroblastoma cannot be overemphasised.

Constitution

Consensus

Low- and Intermediate-Risk Neuroblastomaorder to improve event-free survival [EFS] and overall survival [OS]). Long-term follow-up and comprehensive integration of all new knowledge are still needed to really sort out the best approach for the individual patient according to all risks. In this review, we will present evolution in time and current approaches.

heart-murmur

狗窝

Neuroblastoma Pathogenesisdisease and a clinical challenge; however, few insights into the pathogenesis of these specific forms and the genes involved in metastasis have been identified so far. This is due at least in part to the difficulty of developing relevant preclinical neuroblastoma models presenting with metastasis. V

stress-test

Image-Defined Risk Factorsnes have been established to optimize and uniform the radiological descriptions, including specific definitions recommended. The value of IDRF has been confirmed by the fact that they represent the basis of a pretreatment staging system (INRGSS), mainly important for localized NBL. INRGSS was develo