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Titlebook: Neurobiology of Acetylcholine; Nae J. Dun,Robert L. Perlman Book 1987 Plenum Press, New York 1987 attention.biology.neurobiology

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Distribution of Cholinergic Neurons in Human Brainvertheless, for many years information regarding cholinergic pathways, particularly in the central nervous system, lagged behind several other neurotransmitters because of technical difficulties in cellular localization of cholinergic structures. Initial information came from measurements of the eff
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Development of the Acetylcholine Receptor Clusters Induced by Basic Polypeptides in Cultured Muscle tron–microscopic (EM) autoradiography, it has been estimated that there are over ten thousand AChR per square micron within the AChR cluster (1). This concentration of AChR is essential for the efficiency of the synaptic transmission and is the key event in the development of the postjunctional memb
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Characteristics of Cholinergic Synapses in Neuroblastoma Myotube Co-Culturesth biochemical and electrophysiological experiments on a relatively homogeneous cell population and to manipulate the state of cellular differentiation by suitable alterations of culture conditions. Among the better characterized cell lines are those derived from the C-1300 neuroblastoma tumor (Augu
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The Application of Immunochemical Techniques to the Study of Cholinergic Functionrom myotubes (Fig. lb).. Their ventral (under) surfaces are almost completely (80%) covered with synapses resembling - not unexpectedly - neuromuscular junctions; the transmitter is acetylcholine3. A single average-sized fish contains about 400 g of electric organ which in turn contains 500–1000 tim
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The Effect of AH 5183 (2-(4-Phenylpiperidino)-Cyclohexanol) on Acetylcholine Synthesis and Release inaptic vesicles isolated from the electric organ of Torpedo. Toll and Howard (1980) and Melega and Howard (1984) reported that AH 5183 inhibited the loading of ACh into storage vesicles in PC 12 cells without affecting the vesicular storage of preformed ACh. They found no effect on choline uptake or
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