Titlebook: Neurobiological Mechanisms of Opiate Withdrawal; Rafael Maldonado,Luis Stinus,George F. Koob Book 1996 Springer-Verlag Berlin Heidelberg 1

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Interferons

Animal Models of Opiate Dependence, its measurable actions. However, tolerance develops to many different effects of morphine, to different degrees and at different rates. Moreover, some effects seem to be unchanged while others increase after repeated opiate administration. Thus, these adaptive mechanisms, which develop for each mor

Endometrium

Neurophysiology of Opiate Dependence,zation rates by the 2-deoxy-D-[1-.C] glucose is a method that provides an index of regional functional activity in the central nervous system.. This method has been used to investigate the functional cerebral anatomy of both spontaneous and naloxone-precipitated morphine withdrawal. A selective and

是他笨

Neurochemistry of Opiate Dependence,ous regulation affecting the endogenous opioid system and heterologous regulation that affects other neurotransmitter systems.. Numerous nonopioid systems have been proposed to participate in this heterologous regulation. Thus, changes in several classical neurotransmitters and neuropeptides have be

Irksome

Neuropsychopharmacology of Opiate Dependence,d by a lowered responsiveness to the drug, coupled with dependence which is evidenced by a heightened responsiveness to opiate antagonists and disturbances upon withdrawal of drugs. These phenomena result from cellular and molecular mechanisms, considered as adaptive processes that develop in respon

STRIA

信徒

肥料

flimsy

compel

Treatment of Opiate Withdrawal,There are a variety of procedures for opiate detoxification and treatment of opiate withdrawal, and these fall into two major classes: opiates and nonopiates. Opiates include the use of methadone, a long-acting oral analogue, and buprenorphine, a mixed agonist/antagonist. Nonopiates include clonidine (Catapres.).