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Titlebook: NeuroPsychopharmacotherapy; Peter Riederer,Gerd Laux,Christian Riederer Reference work 2022 Springer Nature Switzerland AG 2022 Pharmacolo

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Pharmacokinetic and Pharmacodynamic Principlesribed medication and its effect on psychiatric symptoms. This chapter identifies the very likely reasons for this shortcoming of clinical trials: Concentration-effect relationships becomes less and less clear-cut as one proceeds from simple outcomes that are very much upstream in the biologic chain
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Psychopathology: Rating Scales for the Assessment of Mental Status Rating scales serve above all to record the severity of the psychopathology and side effects. In studies, especially observer-rating scales are the most important outcome criteria. However, the use of interviews and rating scales requires a comprehensive training.
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Xenobiotic Interactions in Psychopharmacotherapy: Classification and Handlingica), such as food as well as legal (tobacco smoke, caffeine, alcohol) and illegal drugs. Therefore, the medical challenge is not to just avoid any interaction. Instead, the physician faces the question how to proceed with drug treatment in the presence of such interactions. Based on their medical e
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Adverse Drug Reactions, Intoxications and Interactions of Neuropsychotropic Medicationsdvisable to rely on a single database only, this chapter also contains a comprehensive description of available databases on ADRs, pharmacogenetic profiles of drug metabolism, drug interactions – including pharmacogenetic ones – and toxicologic information on medications.
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