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Titlebook: Neural Transplantation Methods; Stephen B. Dunnett,Alan A. Boulton,Glen B. Baker Book 2000 Humana Press 2000

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书目名称Neural Transplantation Methods
编辑Stephen B. Dunnett,Alan A. Boulton,Glen B. Baker
视频video
丛书名称Neuromethods
图书封面Titlebook: Neural Transplantation Methods;  Stephen B. Dunnett,Alan A. Boulton,Glen B. Baker Book 2000 Humana Press 2000
描述we might seek alternative sources of donor tissues. Genetic en- neering, expansion of precursor cells, generation of immortalized cell lines, and transplantation between species are all under active investigation. Although significant difficulties remain for each of these alternatives, the problems appear soluble and relevant knowledge is expanding rapidly. As we enter the twenty-first century, the place of neural tra- plantation in experimental neuroscience is continuing to evolve. Rather than being a topic in its own right, neural transplantation increasingly serves as just another technique in the researcher‘s armory--alongside lesions, pharmaceuticals, gene transfer, and a variety of other techniques--for the experimental manipulation of brain structure and function. This is particularly true for studies of degeneration, plasticity, regeneration, and recovery of function in the nervous system, topics of increasing importance as experimental neurobiology is required to serve the higher needs of neurological and mental health in aging societies. Within this evolving context, Neural Transplantation Methods seeks to serve a particular need: to provide experimental neu- scientists w
出版日期Book 2000
版次1
doihttps://doi.org/10.1007/978-1-59259-690-4
isbn_softcover978-1-61737-191-2
isbn_ebook978-1-59259-690-4Series ISSN 0893-2336 Series E-ISSN 1940-6045
issn_series 0893-2336
copyrightHumana Press 2000
The information of publication is updating

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Neural Transplantation in Parkinsonian Primates.; .; .; .). The continued importance of animal studies in the development of neural transplantation techniques is well recognized (.; Kordower et al., 1998). The role of primate studies is to address those issues that cannot readily be resolved in rodents.
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Book 2000splantation between species are all under active investigation. Although significant difficulties remain for each of these alternatives, the problems appear soluble and relevant knowledge is expanding rapidly. As we enter the twenty-first century, the place of neural tra- plantation in experimental
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Pregraft Tissue Storage Methods for Intracerebral Transplantationt of tissue over long distances, extensive microbiological and immunological testing, and even pretreatment of the graft tissue with neurotrophic or neuroprotective factors, would all require expansion of the time interval between the actual dissection of the donor tissue and its implantation in the host brain.
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Preparation of Cell Suspensions for Transplantationl vascularization of the transplants (e.g., previous cavitation); multiple grafts can be placed within any individual animal/patient; the co-grafting of several tissue types is more easily realized using this technique; and suspension grafts enable an assessment to be made of the number and viability of cells being implanted.
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