Titlebook: Neural Functions of the Delta-Opioid Receptor; Ying Xia Book 2015 Springer International Publishing Switzerland 2015 delta opioid receptor

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,Current Research on the δ-Opioid Receptor: From Neuroprotection Against Hypoxia/Ischemia to Broad Nnificant progress. Our first finding showed that DOR is an endogenous inhibitor of sodium channels, and DOR signaling is involved in the maintenance of ionic homeostasis stabilization in physiological conditions as well as under hypoxic/ischemic stress. DOR activation upregulates the expression of a

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,Evolutionary Distribution of the δ-Opioid Receptor: From Invertebrates to Humans,ively denser at first and distributed in a more homologous manner in the zebrafish, with only a light rostral-to caudal pattern of DOR distribution apparent. This rostral-caudal pattern becomes increasingly pronounced and heterogeneous in turtles, more evident in rats, and even more prominent in hum

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,The Role of δ-Opioid Receptors in Brain Ionic Homeostasis Under Physiological Condition,ensive interaction with ion channels, receptors, and transporters. DOR can regulate the release of many neurotransmitters, modify neuronal electrical activities and synaptic plasticity, and thereby tightly regulates ion homeostasis in neural activities. In this chapter, we will focus on the regulati

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,The Delta-Opioid System in the Brain: A Neglected Element in Parkinson’s Disease?,opment and clinical trials. The abundant expression of opioid receptors and their endogenous ligands, especially those for the δ-opioid system within the basal ganglia, has attracted much attention for its contribution to neurodegenerative diseases such as PD. In this article, we first discussed the

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