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Titlebook: Neoplasms of the Liver; Kunio Okuda,Kamal G. Ishak Book 1987 Springer Japan 1987 cancer.carcinogenesis.carcinoma.hepatitis.Hepatitis B.hep

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发表于 2025-3-21 16:58:28 | 显示全部楼层 |阅读模式
书目名称Neoplasms of the Liver
编辑Kunio Okuda,Kamal G. Ishak
视频video
图书封面Titlebook: Neoplasms of the Liver;  Kunio Okuda,Kamal G. Ishak Book 1987 Springer Japan 1987 cancer.carcinogenesis.carcinoma.hepatitis.Hepatitis B.hep
描述Primary liver cancer is a rather unusual malignancy in that the incidence varies tremendously from one geographical area to another. While relatively uncom­ mon in Western countries, it is the most prevalent malignant neoplasm in Southeast Asia, South Africa, and many other regions; in all, the countries in which primary liver cancer is very prevalent account for more than two-thirds of the world‘s population. In China alone, approximately 100 000 people die every year from primary liver cancer, mostly hepatocellular carcinoma. The incidence is rising in some countries, especially Japan, where it has doubled among males in the past 15 years or so, a staggering and puzzling trend. Since the demonstration of an etiological relationship between hepatitis B virus infection and hepatocellular carcinoma, intensive research has been con­ ducted in an effort to elucidate the role of the virus in hepatocarcinogenesis. Though much progress has been made, a full understanding of the molecular events leading to malignant transformation of the hepatocyte will probably require many more years of rigorous investigation. Chemical carcinogens and several industrial pollutants may also be involved i
出版日期Book 1987
关键词cancer; carcinogenesis; carcinoma; hepatitis; Hepatitis B; hepatocellular carcinoma; liver; liver cancer; li
版次1
doihttps://doi.org/10.1007/978-4-431-68349-0
isbn_softcover978-4-431-68351-3
isbn_ebook978-4-431-68349-0
copyrightSpringer Japan 1987
The information of publication is updating

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Benign Tumors of the Liverof uncertain pathogenesis. They have diverse clinical manifestations that parallel their pathological features. The classification of benign hepatic tumors (Table 8.1), based on their principal histological features, is adapted from several previously published reviews [1-4].
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Malignant Mesenchymal Tumors of the Liverf the 405 primary malignant tumors collected by Edmondson and Peters [1] 1.2% were sarcomas. A survey of death certificates, notoriously unreliable, in the United States from 1966 to 1973 disclosed 205 hepatic sarcomas [2]; the cases included angiosarcoma (36%), leiomyosarcoma (12%), fibrosarcoma (7%), and unspecified sarcomas (44%).
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Hepadna Viruses and Hepatocarcinogenesis35% to 90% in patients with HCC [2]. When additional serum testings for anti-HBs and anti-HBc (core) were included, HBV infection rates reached 75%–81% in Africa [3], the USA [4], and Japan [5] (Table 3.1). These data indicate that the majority of patients with HCC had a previous infection or current antigenemia.
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Hepatocellular Carcinoma in Hemochromatosisiated with a progressive increase in body iron stores. Hemochromatosis is now widely used to refer to this inherited disease, and the term “secondary iron overload” is used to refer to iron overload resulting from hematological defects or blood transfusions.
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Epidemiology of Hepatocellular Carcinoma common malignant tumor among males in western, middle, and eastern Africa, the second most common in southern Africa and Southeast Asia, and the third most common among males in China. It is a relatively rare tumor in most parts of America, Europe, northern Africa, and middle and eastern Asia [1].
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