书目名称 | Natural Products from Actinomycetes | 副标题 | Diversity, Ecology a | 编辑 | Ravishankar V. Rai,Jamuna A. Bai | 视频video | | 概述 | Presents secondary metabolites coding silent biosynthetic gene clusters in Actinomycetes genome.Describes new approaches such as metagenomics for natural product discovery from Actinomycetes.Contains | 图书封面 |  | 描述 | .This book provides in-depth information about the ecology, diversity and applications of Actinomycetes. The book is divided into two major parts. The first part discusses the diversity, chemical biology and ecology of Actinomycetes. It also covers the discovery of natural products from soil, endophytic and marine-derived Actinomycetes. It includes natural product discovery, chemical biology, new methods for discovering secondary metabolites, structure elucidation and biosynthetic research of natural products. The chapters in this part focus on the effects of biological and chemical elicitation at molecular level on secondary metabolism in Actinomycetes. The second part of the book discusses genomic and synthetic biology approaches in Actinomycetes drug discovery. This part includes chapters focused on the application of metabolic engineering to optimize natural product synthesis and the use of omics data in engineering of regulatory genes. It covers the advanced tools of synthetic biology and metabolic engineering including cluster assembly, CRISPR/Cas9 technologies, and chassis strain development for natural product overproduction in Actinomycetes. It describes the use of bioinfo | 出版日期 | Book 2022 | 关键词 | Actinobacteria; Actinomycetes; Antimicrobial; Genome Mining; Polyketide Synthase Gene; Secondary Metaboli | 版次 | 1 | doi | https://doi.org/10.1007/978-981-16-6132-7 | isbn_softcover | 978-981-16-6134-1 | isbn_ebook | 978-981-16-6132-7 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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