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Titlebook: Natriuretic Hormone; Herbert J. Kramer (Assoc. Professor of Medicine),F Conference proceedings 1978 Springer-Verlag Berlin Heidelberg 1978

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Conference proceedings 1978ing the possibility of assem­ bling scientists who are concerned with and interested in the problem of a possible humoral natriuretic activity. Work has been done on this topic in different parts of the world, partially with different methods and sometimes also with different and contlict­ ing resul
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Introductione on this topic in different parts of the world, partially with different methods and sometimes also with different and conflicting results. And thus we thought it could be very beneficial to have personal discussions with all of you so as to reach a consensus of opinion on how studies should be continued.
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Antinatriferic and Natriuretic Activities in Human Plasma Following Acute and Chronic Salt-Loadinghave shown that one fraction of plasma obtained following acute expansion of the ECV, which follows the elution of salts from the Sephadex G-25 column, significantly decreases both PD and SCC in the isolated frog skin assay [9, 14, 15, 17].
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Natriuretic Factor in Chronic Uremiaremic model relates to the progressive increase in natriuretic forces responsible, as glomerular filtration rate (GFR) decreases, for the regulated excretion of sodium in chronic renal disease [5]. These natriuretic forces may involve a natriuretic hormone.
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Column Chromatography of Plasma Antinatriferic Activityluid (ECF) volume and decrease following contraction of the ECF volume. Accordingly, our data are compatible with the interpretation that this factor in some way mediates the natriuretic effect of both acute and chronic expansion of ECF volume.
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Acute Hypophysectomy - a Model for the Study of Hormonal Mechanisms of Natriuresisand pathophysiology of body fluid volume has failed to become an attractive topic. The only way to improve the situation may be clear-cut direct evidence that such a hormone exists. I hope we are closer to this goal at the end of the present workshop.
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