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Titlebook: Nanoscale Imaging and Characterisation of Amyloid-β; Claire Louisa Tinker-Mill Book 2016 Springer International Publishing Switzerland 201

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Nanoscale Imaging and Characterisation of Amyloid-β
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978-3-319-81907-5Springer International Publishing Switzerland 2016
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Nanoscale Imaging and Characterisation of Amyloid-β978-3-319-39534-0Series ISSN 2190-5053 Series E-ISSN 2190-5061
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Springer Theseshttp://image.papertrans.cn/n/image/660934.jpg
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https://doi.org/10.1007/978-3-319-39534-0AFM Imaging of Amyloid-beta; Nanomechanical Characterisation; Alzheimer‘s Disease and AFM; Aggregation
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Introduction,A brief introduction to the work in this thesis, including the rationale behind the work and the challenges faced. The reasoning behind the focus on Alzheimer’s disease and the application of SPM and other physical techniques to this disease are given, in addition to an overview of these techniques.
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,Alzheimer’s Disease and the Aggregation of Amyloid β,This chapter focuses on Alzheimer’s disease, which is caused by the accumulation and aggregation of Aβ. The neuropathology and biochemical processes behind the disease are discussed along with therapeutic strategies. It is the aim of this chapter, to convey the seriousness of AD as a worldwide disorder and explore it’s pathology.
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Conclusion and Future Perspectives,This chapter summarises the key conclusions from each chapter of results, while also positioning these in the context of future work to be conducted.
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