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Titlebook: NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therap; Zofia Zukowska,Giora Z. Feuerstein B

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https://doi.org/10.1007/3-7643-7417-9biology; circulation; diseases; endothelium; genes; homeostasis; metabolic disorder; metabolism; molecular b
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Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctionsesynaptic release of ATP and NA. Sympathetic reflexes regulate human vascular resistance, where NPY plays a modulator role of paramount importance following increased sympathetic discharges, such as stress and vascular disease.
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NPY in alcoholism and psychiatric disordersr treatment designs. Selective Y2 receptor antagonists and/or Y1 agonists that are peripherally available and effectively penetrate the CNS are possible candidates. In conclusion, the NPY system offers attractive targets for development of future treatments for depression, anxiety, and alcohol dependence.
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