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Titlebook: NBC Risks Current Capabilities and Future Perspectives for Protection; Torsten Sohns,Victor A. Voicu,Harald Kempf Book 1999 Springer Scien

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Selectivity and Protective Activity of Muscarinic Receptor’s Antagonists in Organophosphates Poisoniods to treat organophosphorus poisoning is a significant medical problem. Among many drugs assigned for treatment of organophosphorus intoxication, an important place belongs to muscarinic antagonists (M-antagonists). At the same time, it is necessary to take account of the specific type of muscarin
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Reactivators, from Classic to a New Generation as 2PAM, 2PAS, TMB-4 and toxogonin are being applied on a wide range and have been examined in detail. The difficulty in reactivation of the ChE activity and slight antidote effect concerning intoxication with some organophosphorus compounds (OPC), are some of the reasons for continuing the examina
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Reactivation of Organophosphorus — Inhibited Human Erythrocyte-Acetylcholinesterase by Oximes in vit these results to humans is hampered by species differences. Besides atropine, oximes are considered as main antidotes. The most important effect of these compounds is the reactivation of inhibited acetylcholinesterase (AChE). The reactivating potency of oximes can be investigated with human materia
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