书目名称 | NADPH Oxidases Revisited: From Function to Structure | 编辑 | Edgar Pick | 视频video | | 概述 | Unique comprehensive state-of-the-art-work on NADPH oxidases.Offers knowledge on molecular function and activation.Discusses the pathophysiological role of NADPH oxidases | 图书封面 |  | 描述 | .This book provides a unique, comprehensive, and up-to-date overview of the various NADPH oxidases and narrates the history of their discovery, biochemical characteristics, genetics, molecular structure, and multiple functions in health and disease. It covers the subject in a manner that serves both the expert and the novice researcher in the field..The book starts with an overview of the major milestones in the discovery of the archetypical NADPH oxidase, known as cytochrome .b.558., and its cytosolic regulators. This is followed by personal recollections by pioneers of the field, descriptions of the work of the major figures of the past by their followers, and a rendering of the history of the discovery of the Nox family. The central section of the book consists of chapters devoted specifically to an in depth description of the individual members of the Nox family, and is followed by chapters focused on the modulators of their function. A subsequent section comprises chapters dealing with methodologies of Nox research, interaction with other proteins, and Nox inhibitors. A distinct section of the book deals with non-mammalian Noxs, from amoeba to zebrafish. Subsequent chapters fo | 出版日期 | Book 2023 | 关键词 | Activation of Noxes; Chronic Granulomatous Disease; Cytochrome b; Functional NADPH Oxidase Complex; NADP | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-23752-2 | isbn_softcover | 978-3-031-23754-6 | isbn_ebook | 978-3-031-23752-2 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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