书目名称 | Myocardial Protection and the KATP Channel |
编辑 | Derek M. Yellon (Professor of Cellular Cardiology, |
视频video | |
丛书名称 | Developments in Cardiovascular Medicine |
图书封面 |  |
描述 | The ATP-sensitive potassium channel (K.ATP.) wasdiscovered in 1983. Since then, an enormous amount of research hasbeen undertaken to characterize it in detail. This volume consolidatesboth the current knowledge and most recent advances on the subject,and its relationship to myocardial protection. To this end, theeditors have assembled investigators at the forefront of ongoing basicand clinical research to provide scholarly and candid commentsconcerning each of the pertinent issues, including: a comprehensivereview of the biology of the channel with respect to thestructure-activity relationship as well as overall chemistry ofthe channel; the role of opening this channel and its effect on smoothmuscle (covering both the effects on myocardial stunning and itsability to protect against myocardial infarction); the relationship ofK.ATP. channel opening and the protection to the myocardiumafforded by the phenomenon of ischemic preconditioning; therelationship between the K.ATP. channel and electrophysiologicalconsequences with specific reference to arrhythmogenicity; and theclinical implications of the use of agents that mimic the opening ofthis channel, with reference to its protective n |
出版日期 | Book 1995 |
关键词 | biology; chemistry; clinical research; medicine; muscle; myocardial infarction; pathology; pharmacology; res |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4613-0453-1 |
isbn_softcover | 978-1-4613-8055-9 |
isbn_ebook | 978-1-4613-0453-1Series ISSN 0166-9842 |
issn_series | 0166-9842 |
copyright | Kluwer Academic Publishers 1995 |