书目名称 | Myeloid Leukemia |
副标题 | Methods and Protocol |
编辑 | Harry Iland,Mark Hertzberg,Paula Marlton |
视频video | |
概述 | Includes supplementary material: |
丛书名称 | Methods in Molecular Medicine |
图书封面 |  |
描述 | A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered. |
出版日期 | Book 2006 |
关键词 | DNA; cell; classification; leukemia; stem cell; stem cell transplantation; transplantation |
版次 | 1 |
doi | https://doi.org/10.1385/1597450170 |
isbn_softcover | 978-1-60761-456-2 |
isbn_ebook | 978-1-59745-017-1Series ISSN 1543-1894 Series E-ISSN 1940-6037 |
issn_series | 1543-1894 |
copyright | Humana Press 2006 |