书目名称 | Multiple Drug Resistance in Cancer 2 | 副标题 | Molecular, Cellular | 编辑 | Martin Clynes | 视频video | | 图书封面 |  | 描述 | Resistance to chemotherapy, and especially multi-drugresistance, represents a significant barrier to the successfultreatment of cancer. This multi-author volume brings together a widerange of up-to-date reviews on different aspects of our knowledge ofdrug-resistance mechanisms, written by experts in the different areas.Particular attention is paid to recently discovered mechanismsrelating to oncogene expression and in particular to proteins involvedin regulation and execution of apoptosis. Other important topicscovered include DNA repair, topoisomerases, cell cycle control,oxygenation and vascularisation of tumours, LRP, intermediate filamentproteins and low-level resistance. Recent developments inunderstanding the role of efflux pumps (P-170, MRP) in multi-drugresistance are also reviewed. This book will be useful to cliniciansand scientists working in the areas of chemotherapy, drug resistance,DNA repair and apoptosis research. | 出版日期 | Book 1998 | 关键词 | DNA; Nucleotide; apoptosis; gene expression; proteins; transcription | 版次 | 1 | doi | https://doi.org/10.1007/978-94-017-2374-9 | isbn_softcover | 978-90-481-5108-0 | isbn_ebook | 978-94-017-2374-9 | copyright | Springer Science+Business Media B.V. 1998 |
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