书目名称 | Multiple Drug Resistance in Cancer |
副标题 | Cellular, Molecular |
编辑 | Martin Clynes |
视频video | |
图书封面 |  |
描述 | This book is an up-to-date review of current knowledge in thefield of multiple drug resistance in human cancer. The literature upto the middle of 1993 is surveyed in specialist chapters written bydifferent experts. Topics covered include the molecular genetics,cytogenetics and biochemistry of the.mdr. genes andP-glycoprotein; alternative transport proteins in MDR; topoisomerasesI and II; cytochrome p450-enzymes and glutathione-.S.-transferases in MDR; cellular models for MDR in solid tumoursand haemopoietic tumours; immunochemical and molecular biologicaltechniques for detection of MDR-related gene expression; and clinicaland pharmacological strategies to circumvent resistance. The bookbrings together a new combination of approaches to this seriousclinical problem. . |
出版日期 | Book 1994 |
关键词 | biochemistry; cancer; chemistry; cytochrome P450; cytogenetics; drug; drug resistance; gene expression; gene |
版次 | 1 |
doi | https://doi.org/10.1007/978-94-011-0826-3 |
isbn_softcover | 978-94-010-4355-7 |
isbn_ebook | 978-94-011-0826-3 |
copyright | Springer Science+Business Media Dordrecht 1994 |