书目名称 | Multifunctional Gold Nanostars for Cancer Theranostics | 编辑 | Yang Liu | 视频video | | 概述 | Nominated as an outstanding Ph.D. thesis by the Duke University, USA.Outlines the development of theranostic gold nanostars (GNS) for cancer diagnostics and therapy.Analyzes in vivo the efficient comb | 丛书名称 | Springer Theses | 图书封面 |  | 描述 | .This thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. .Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients’ overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan – a superior non-invasive imaging modality – in a mouse animal model. In addition, d | 出版日期 | Book 2018 | 关键词 | Multifunctional Nanoprobe; Gold Nanostars (GNS); Nanomedicine; Cancer Theranostics; Cancer Imaging; Cance | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-74920-4 | isbn_softcover | 978-3-030-09104-0 | isbn_ebook | 978-3-319-74920-4Series ISSN 2190-5053 Series E-ISSN 2190-5061 | issn_series | 2190-5053 | copyright | Springer International Publishing AG, part of Springer Nature 2018 |
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