书目名称 | Mononitrate II | 编辑 | D. G. Julian (Medical Director),R. Rittinghausen ( | 视频video | | 丛书名称 | International Boehringer Mannheim Symposia | 图书封面 |  | 描述 | A group of internationally renowned experts in the field of cardiology and pharmacology discuss the latest state-of-art in nitrate therapy. Particular emphasis is put on isosorbide-5-mononitrate (IS-5-MN). The pharmacology, pharmacokinetics, and pharmacodynamics of such therapy are described as well as its methods of action, including such aspects as denitration, increase in cyclic guanosine-monophosphate, and the endothelium derived relaxant factor. The clinical part of the book deals with dosage, effectiveness, and the development of tolerance. The effect on ventricular hemodynamics and vasospastic angina is considered. Comparative studies of IS-5-MN with other nitrates, calcium antagonists, and beta blockers using exercise testing, Holter ECG recording, and invasive techniques provide a comprehensive survey of IS-5-MN treatment of coronary heart diseases. Also summarized is the state-of-the-art regarding silent myocardial ischemia, its treatment, and models of pain perception. .Mononitrate II. is the follow-up volume to the previous book on mononitrates in the series .International Boehringer Mannheim Symposia.. | 出版日期 | Conference proceedings 1987Latest edition | 关键词 | cardiology; coronary heart disease; electrocardiogram (ECG); heart; heart disease; hemodynamics; pharmacod | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-72689-7 | isbn_softcover | 978-3-540-17832-3 | isbn_ebook | 978-3-642-72689-7Series ISSN 0173-0282 | issn_series | 0173-0282 | copyright | Springer-Verlag Berlin Heidelberg 1987 |
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