| 书目名称 | Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy |
| 副标题 | Targeted Therapies t |
| 编辑 | Benjamin Bonavida |
| 视频video | |
| 概述 | Describes the main mechanisms that govern tumor cell resistance to apoptotic stimuli.Demonstrates the identification of existing agents or the development of new agents that can serve as sensitizing a |
| 丛书名称 | Resistance to Targeted Anti-Cancer Therapeutics |
| 图书封面 |  |
| 描述 | This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors. |
| 出版日期 | Book 2013 |
| 关键词 | ABC Drug transporters; HPC1; apoptosis; chemoresistance; cytotoxics; β1 Integrins; antibacterial drug resi |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4614-7070-0 |
| isbn_softcover | 978-1-4899-8841-6 |
| isbn_ebook | 978-1-4614-7070-0Series ISSN 2196-5501 Series E-ISSN 2196-551X |
| issn_series | 2196-5501 |
| copyright | Springer Science+Business Media New York 2013 |
发表于 2025-3-21 19:59:29
