| 书目名称 | Molecular Interactions in Bioseparations | | 编辑 | That T. Ngo | | 视频video | http://file.papertrans.cn/639/638303/638303.mp4 | | 图书封面 |  | | 描述 | Rapid advances in molecular biology have accelerated the production of a great number of protein-based therapeutic agents. The major cost in producing these proteins appears to be associated with their purification from the complex mixture of the crude extract. A major challenge to the protein biochemist and the biochemical engineer is the development of rapid, efficient, and cost-effective purification systems. This volume presents state-of-the-art reviews of current methods used in the purifica tion of biological macromolecules that are based on molecular interactions. Thus, the major emphasis is placed on affinity-related techniques. Part I provides a general introduction to affinity chromatography and includes a chapter describing an interesting new technique called "slalom chromatography" for DNA fractionations. Affinity chromatography using molecules of biological origin as the affinity ligand is covered in Part II. Part III describes the use of a special class of biomolecules, antibodies, as affinity ligands. Affinity chromatography with biomimetic ligands is discussed in Part IV. Newer concepts and their applications in bioseparation are presented in Part V. Part VI covers | | 出版日期 | Book 1993 | | 关键词 | bacteria; chromatography; polymer; protein; receptor | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4899-1872-7 | | isbn_softcover | 978-1-4899-1874-1 | | isbn_ebook | 978-1-4899-1872-7 | | copyright | Springer Science+Business Media New York 1993 |
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