| 书目名称 | Molecular Genetics of Inflammatory Bowel Disease | | 编辑 | Mauro D‘Amato,John D Rioux | | 视频video | | | 概述 | Provides a complete review of existing knowledge of molecular genetics in inflammatory bowel diseases.Highlights the latest discoveries from molecular and genome-wide association studies.Gives insight | | 图书封面 |  | | 描述 | Research in Crohn’s disease (CD) and ulcerative colitis (UC), together known as the inflammatory bowel diseases (IBD), has truly seen a revolution in the last 5-10 years. This book examines how these genetic discoveries have led to the identification of biological functions not previously associated with IBD pathophysiology (e.g. autophagy), how multiple genetic risk factors for IBD converge on given biological functions and that together the identified variants in these genes have predisposing and protective roles (e.g. the multiple variants in the receptor for the IL23 cytokine and its signaling cascade), and how having such a large number of known genetic risk factors has changed our understanding not only about the genetic and molecular overlap between CD and UC, but also between these diseases and other chronic inflammatory diseases (e.g. psoriasis, multiple sclerosis, type 1 diabetes and many others). | | 出版日期 | Book 20131st edition | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4614-8256-7 | | isbn_softcover | 978-1-4939-4256-5 | | isbn_ebook | 978-1-4614-8256-7 | | copyright | Springer Science+Business Media New York 2013 |
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发表于 2025-3-21 17:18:10
