书目名称 | Molecular Genetics of Endometrial Carcinoma |
编辑 | Lora Hedrick Ellenson |
视频video | |
概述 | Explains the metabolic and hormonal influences of endometrial carcinoma.Gives perspectives on traditional approaches and next-generation sequencing in the molecular profiling of endometrial carcinoma. |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists,from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma.. |
出版日期 | Book 2017 |
关键词 | PTEN/ PI3K; endometrial cancer; next generation sequencing; signaling pathways; molecular genetics; gene |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-43139-0 |
isbn_softcover | 978-3-319-82747-6 |
isbn_ebook | 978-3-319-43139-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |