| 书目名称 | Molecular Evolution of the Major Histocompatibility Complex | | 编辑 | Jan Klein,Dagmar Klein | | 视频video | | | 丛书名称 | Nato ASI Subseries H: | | 图书封面 |  | | 描述 | From molecules to populations and back In biology, the most vigorous organisms often ensue from a union of two disparate, pure lines. In science, too, laws of hybrid vigor seem to operate at the interface between two disciplines, an interface that often proves to be fertile ground for germinating concepts and new outlooks. The fringes of research into the major histocompatibility complex (Mhc) have provided such an interface several times in the past and the encounters have invigorated fields such as transplantation biology, cellular immunology, and immunogenetics. In the last few years, a new interface has been emerging between Mhc and evolutionary genetics, and particularly the branch of evolutionary genetics dealing with molecular evolution. Mhc research relies upon molecular evolutionary genetics, with its grand superstructure of mathematical formulations, to come to grips with the events leading to and maintaining the Mhc polymorphism. Without the armament of rigorous statistical procedures developed by evolutionary geneticists, the intricate relationships among Mhc genes cannot be resolved. It will undoubtedly be a molecular geneticist who is the final arbiter in the dispute | | 出版日期 | Conference proceedings 1991 | | 关键词 | Phylogenie; activation; antigen; antigen presentation; autoimmune disease; chromosome; evolution; gene; hist | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-84622-9 | | isbn_softcover | 978-3-642-84624-3 | | isbn_ebook | 978-3-642-84622-9Series ISSN 1010-8793 | | issn_series | 1010-8793 | | copyright | Springer-Verlag Berlin Heidelberg 1991 |
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发表于 2025-3-21 17:21:57
