| 书目名称 | Molecular Biology of the Parathyroid |
| 编辑 | Tally Naveh-Many |
| 视频video | |
| 概述 | Molecular Biology of the Parathyroid is the first book to describe recent studies and discoveries in the field in detail..This title is essention reading for enocrinologists and all researchers workin |
| 丛书名称 | Molecular Biology Intelligence Unit |
| 图书封面 |  |
| 描述 | aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using gene |
| 出版日期 | Book 2005 |
| 关键词 | G proteins; bone; physiology; regulation; signaling pathways; thyroid hormone; tissue |
| 版次 | 1 |
| doi | https://doi.org/10.1007/0-387-27530-4 |
| isbn_softcover | 978-1-4419-3415-4 |
| isbn_ebook | 978-0-387-27530-7Series ISSN 1431-0414 |
| issn_series | 1431-0414 |
| copyright | Springer-Verlag US 2005 |
发表于 2025-3-21 18:29:43
