书目名称 | Molecular Biology of Long Non-coding RNAs | 编辑 | Ahmad M. Khalil,Jeff Coller | 视频video | | 概述 | Brings together key experts in the field of lncRNAs.Has appeal for basic scientists and clinicians.Focuses on the recently discovered, and less understood, class of long non-coding RNAs | 图书封面 |  | 描述 | Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Discovering these functions has been the result of intense research done of the last few years, and lncRNA research has had several critical developments during that time. This book will consolidate these ideas and models to better examine the most important issues in lncRNA biology. This will include critical studies that have led to the discovery and annotation of lncRNAs in numerous species, and the molecular mechanisms for a few lncRNA that have begun to emerge. | 出版日期 | Book 20131st edition | 关键词 | dysregulation; gene regulation; lncRNAs; long non-coding RNAs | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4614-8621-3 | isbn_softcover | 978-1-4939-4528-3 | isbn_ebook | 978-1-4614-8621-3 | copyright | Springer Science+Business Media New York 2013 |
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