书目名称 | Molecular Biology of Human Cancers | 副标题 | An Advanced Student‘ | 编辑 | Wolfgang Arthur Schulz | 视频video | | 概述 | Provides an overview on the cancer research field.Interdisciplinary textbook that can serve as an introduction to facts, concepts and frontiers of research on the molecular biology of human cancer.Con | 图书封面 |  | 描述 | .Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. Insights have also been gained into the molecular mechanisms underlying carcinogenesis by chemical, physical, and biological agents and into inherited susceptibility to cancer. ..Accordingly, Part I of the book presents many of the molecules and mechanisms generally important in human cancers. Following an overview on the cancer problem, individual chapters deal with cancer genetics and epigenetics, DNA damage and repair, oncogenes, tumor suppressors, regulatory pathways in cancer, apoptosis, cellular senescence, tumor invasion, and metastasis...A consensus is emerging that while these common mechanisms and molecules are all relevant to human cancers, in each cancer type (or even subtype) a selection of them are extremely important. For selected cancers, the route from genetic and epigenetic changes to their biological and clinical behavior can already be traced. Part II of the boo | 出版日期 | Textbook 20071st edition | 关键词 | apoptosis; carcinoma; molecular, cancer, human cancers, biology, Cancer, Oncology,; senescence; tissue | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4020-3186-1 | isbn_ebook | 978-1-4020-3186-1 | copyright | Springer Science+Business Media B.V. 2007 |
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