| 书目名称 | Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors |
| 编辑 | Mohan K. Raizada,Derek LeRoith |
| 视频video | http://file.papertrans.cn/639/638068/638068.mp4 |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | This volume addresses a fundamental puzzle in biology and medicine, namely, how does tissue develop, repair and replace itself. The answer appears to lie in growth factors and their regulation. To thrive and survive we need growth factors and this book concentrates on two factors that are related to growth hormone. Growth hormone does not act directly on all tissues, but mediates many of its actions through the release of insulin-like growth factors from the liver. The growth factors were originally called somatomedins by McConaghey and Sledge (1), who discovered that they mediated growth-like effects of growth hormone. However, the factors were purified on the basis of their insulinomimetic actions on fat and muscle and it is their relationship to the insulin family of pep tides that now gives them their name (2,3) of insulin-like growth factors (IGFs). They mediate the actions of. growth hormone on the proteoglycan synthesis of cartilage and produce mitogenic effects in fibroblast cultures. |
| 出版日期 | Book 1991 |
| 关键词 | biology; cartilage; growth; molecular biology; physiology; proteoglycan synthesis; synthesis; tissue |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4684-5949-4 |
| isbn_softcover | 978-1-4684-5951-7 |
| isbn_ebook | 978-1-4684-5949-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
|Archiver|手机版|小黑屋|
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