书目名称 | Molecular Biology and Pathogenesis of Coronaviruses | 编辑 | P. J. M. Rottier,B. A. M. Zeijst,M. C. Horzinek | 视频video | | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the Institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today - to be constructed from essentially three polypeptides - to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, - to generate these subgenomic RNAs through specific fusion of non contiguous sequences, - to mature by budding from intracellular membranes, - to cause persistent infection with neurological involvement and sometimes immunopathological conditons. These and | 出版日期 | Book 1984 | 关键词 | RNA; biology; genetics; infection; membrane; molecular biology; pathogenesis; virology | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4615-9373-7 | isbn_softcover | 978-1-4615-9375-1 | isbn_ebook | 978-1-4615-9373-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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