书目名称 | Molecular Aspects of Myeloid Stem Cell Development |
编辑 | Linda Wolff (Senior Investigator),Archibald S. Per |
视频video | |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | A workshop on "MOLECULAR ASPECTS OF MYELOID STEM CELL DEVELOPMENT" was held at the Historic Inns in Annapolis, MD during April 30-May 3, with approximately 70 persons attend ing. The enormous success of this meeting was attributable to the recent outburst of information generated from two areas of study: transcriptional regulation of developmentally important myeloid genes and molecular dissection of chromosomal abnormalities in human myeloid leukemias. It was reassuring that studies of normal myelopoiesis and abnormal myelopoiesis, as observed in dys plasias and neoplasia, are revealing several interrelated mechan isms of gene regulation. However, great challenges await us as we try to determine how these and other mechanisms in this intricate system orchestrate the ultimate fate of cells e. g. proliferation, differentiation or apoptosis. This volume of Current Topics in Micro biology encapsulates many of the key aspects of the workshop summarizing research over the past few years on the ontogeny and pathology of myeloid cells. Investigations into the complex process of normal myeloid cell . maturation were first made possible through development of in vitro clonigenic assays. |
出版日期 | Conference proceedings 1996 |
关键词 | Knochenmark; apoptosis; cell; chromosome; cytokine; growth; growth factor; hematopoiesis; leukemia; macrophag |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-85232-9 |
isbn_softcover | 978-3-642-85234-3 |
isbn_ebook | 978-3-642-85232-9Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |