书目名称 | Molecular Aspects of Chemotherapy | 副标题 | Proceedings of the T | 编辑 | David Shugar,Wojciech Rode,Edward Borowski | 视频video | | 图书封面 |  | 描述 | While serendipity and random screening continue to fulfil a significant role in the search for new drugs, current remarkable advances in molecular biology and genetics are dictating to a profound extent the approaches employed in their development. Increasing attention is being devoted to investigations of the mechanisms of action of existing drugs, and the sources of undesired side effects, at the molecular level. The information so derived is now extensively applied, with the aid of broad inter disciplinary approaches, both theoretical and experimental, to improvements in existing drugs, and the rational design of new ones. The foregoing comprised the subject matter of the 3rd Inter national Symposium on "Molecular Aspects of Chemotherapy", under the auspices of the International Society of Chemotherapy, and organized by the Committee on Drug Research, Polish Academy of Sciences, and the Department of Biotechnology and Biochemistry, Technical University of Gdansk. This volume includes the texts of the review lectures presented by invited participants on up-to-date achievements, and future perspectives, in molecular mechanisms of inhibition of cellular functions and metabolism, | 出版日期 | Conference proceedings 1992 | 关键词 | DNA; Nucleotide; activation; antibiotics; chemistry; chemotherapy; enzyme; enzymes; membrane transport; metab | 版次 | 1 | doi | https://doi.org/10.1007/978-3-662-02740-0 | isbn_softcover | 978-3-662-02742-4 | isbn_ebook | 978-3-662-02740-0 | copyright | Springer-Verlag Berlin Heidelberg 1992 |
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