| 书目名称 | Modeling Methods for Medical Systems Biology |
| 副标题 | Regulatory Dynamics |
| 编辑 | María Elena‘Álvarez-Buylla Roces,Juan Carlos Martí |
| 视频video | |
| 概述 | Offers an empirical-evidence based methodology to describe the dynamical processes underlying chronic diseases from a gene regulatory networks point of view.Provides state of the art cases-of-study ba |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | .This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progressionof chronic degenerative diseases, using a bottom-up approach.. |
| 出版日期 | Book 2018 |
| 关键词 | Morphogenesis; Systems dynamics; chronic disease; degenerative; biomolecular; immune response; regulation; |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-89354-9 |
| isbn_softcover | 978-3-030-07748-8 |
| isbn_ebook | 978-3-319-89354-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | Springer International Publishing AG, part of Springer Nature 2018 |
发表于 2025-3-21 17:00:39
