书目名称 | Model Systems in Aging |
编辑 | Thomas Nyström,Heinz D. Osiewacz |
视频video | |
概述 | The unique feature of this book is its comparative approach to different genetic model systems.Full text available online for subscribers of the series |
丛书名称 | Topics in Current Genetics |
图书封面 |  |
描述 | .Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process. ..This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and humans, allowing a comparative view on similarities and differences in different genetic model systems. The different model systems are scrutinized in the light of contemporary aging hypothesis, such as the free radical and genomic instability theories. .. |
出版日期 | Book 20041st edition |
关键词 | aging; free radicals; genetic model systems; stress; apoptosis; bacteria; biological functions; development |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-540-37005-5 |
isbn_softcover | 978-3-642-05698-7 |
isbn_ebook | 978-3-540-37005-5Series ISSN 1610-2096 Series E-ISSN 1610-6970 |
issn_series | 1610-2096 |
copyright | Springer-Verlag Berlin Heidelberg 2004 |