| 书目名称 | Mitochondrial DNA | | 副标题 | Methods and Protocol | | 编辑 | Jeffrey A. Stuart | | 视频video | | | 概述 | Covers a wide range of methods for investigating how mitochondrial genetics affect cellular physiology and human health.Details unique experimental approaches for studying mtDNA damage and mutation.An | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .Since the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, our understanding of the basic biology of somatic mtDNA mutations continues to improve. In .Mitochondrial DNA: Methods and Protocols, Second Edition., specialists from eight countries share their expertise, providing detailed protocols for studying many aspects of mtDNA. The volume is divided into three sections, which cover the transduction of information from mtDNA to functionally active respiratory complexes, mitochondrial reactive oxygen species (ROS) production as well as mtDNA damage and its repair, and the identification and quantification of heteroplasmic mtDNA mutations. Written in the highly successful .Methods in Molecular Biology.™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes sections, highlighting tips on troubleshooting and avoiding known pitfalls...Comprehensive and authoritative, .Mitrochondrial DNA: Methods and Protocols, Second E | | 出版日期 | Book 2009Latest edition | | 关键词 | DNA; Damage and repair; Disorders; Heteroplasmic; PCR; Reactive oxygen species (ROS); Replication and tran | | 版次 | 2 | | doi | https://doi.org/10.1007/978-1-59745-521-3 | | isbn_softcover | 978-1-61779-495-7 | | isbn_ebook | 978-1-59745-521-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2009 |
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发表于 2025-3-21 16:20:50
