书目名称 | Mitochondria in Health and in Sickness |
编辑 | Andrea Urbani,Mohan Babu |
视频video | |
概述 | Provides readers the foundational overview on how mitochondrial dysfunction contributes to the development of various neurodegeneration, cancer, and metabolic disorders.Highlights mitochondrial replac |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .Besides bringing together researchers and clinicians from various disciplines to share their scope of research on the seminal role of mitochondria in human disease, this original volume of the book has a broader appeal by exploring the health and disease of mitochondria, with specific emphasis on how mitochondrial dysfunction contributes to the development of various neurodegeneration, cancer, and metabolic disorders. The book also provides a foundational overview of the mitochondrial pathogenic or genetic variants and highlights various analytical tools used in the field of mitochondrial genetics; mitochondrial replacement therapy and strategies geared towards shifting heteroplasmy in individuals with mitochondrial disease; how state-of-the-art omics technologies (proteomics, functional genomics) have been employed to study mitochondrial biology in healthy and disease states; post-translational modifications in the regulation of mitochondrial proteins; and the role of mitochondriain host-pathogen interactions. .Current approaches taken to study steady-state characteristics of mitochondrial structure and function in live mammalian cells in the contexts of normal and diseased state |
出版日期 | Book 2019 |
关键词 | Mitochondrial disease; Mitochondrial dysfunction; Mitochondrial health; Mitochondrial metabolism; Mitoch |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-13-8367-0 |
isbn_softcover | 978-981-13-8369-4 |
isbn_ebook | 978-981-13-8367-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | Springer Nature Singapore Pte Ltd. 2019 |