书目名称 | Mitochondria | 副标题 | The Dynamic Organell | 编辑 | Stephen W. Schaffer,M-Saadeh Suleiman | 视频video | | 概述 | Covers the emergence of mitochondria as an important regulator of cell signaling.Focuses on the pathophysiology of the mitochondria | 丛书名称 | Advances in Biochemistry in Health and Disease | 图书封面 |  | 描述 | The term mitochondrion is derived from Latin, with mitos meaning thread and chondrion meaning granules. Indeed, under the light microscope, mitochondria often appear as rods or granules within the cytoplasm. For decades after initial visualization of mitochondria by light microscopy, mitochondrial function remained clouded. However, with the development of differential centri- gation and electron microscopy, it was discovered that a chief function of the mitochondria was the generation of ATP for the remainder of the cell. For many years, the energy generating function of the mitochondria was considered the primary, if not the sole function of the mitochondria. During that period, inves- gators attempted to obtain information on the mechanism of ATP synthesis and the regulation of electron transport. In the first chapter of the book, Dr. Hassinen summarizes those studies, providing clear pictures on the transformation of reducing equivalents into a proton gradient and the mechanism by which the F F 1 0 ATPase utilizes the proton gradient to generate ATP. He also summarizes the key regulatory steps of the citric acid cycle, which is the major source of reducing equivalents for the e | 出版日期 | Book 2007 | 关键词 | Amino acid; Calcium; DNA; Oxidation; Peroxisom; amino acids; metabolism; molecular biology; physiology; regul | 版次 | 1 | doi | https://doi.org/10.1007/978-0-387-69945-5 | isbn_softcover | 978-1-4419-2418-6 | isbn_ebook | 978-0-387-69945-5Series ISSN 2512-2142 Series E-ISSN 2512-2150 | issn_series | 2512-2142 | copyright | Springer-Verlag New York 2007 |
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