Titlebook: Microtubules; Pierre Dustin Book 1984Latest edition Springer-Verlag Berlin Heidelberg 1984 Nucleotide.antigen.biochemistry.cancer.cell.cel

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General Physiology of Tubulins and Microtubules,MT in the living cell and its abnormalities. The relations of MT with various cell organelles should be considered, and interesting relations with viruses and intracellular parasites will also be described.

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Secretion,lchicine, VLB, VCR, deuterium oxide) and two years following, similar findings concerning the thyroid gland were observed by two groups working independently [100, 162]. Some of this work on the relation of MT to secretory activities was done in Brussels, and led our laboratory to a renewed interest in tubulin and MT poisons.

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MT and MT Poisons in Pathology and Medicine, could be the cause of anomalies of MT. This is particularly apparent in complex structures such a cilia and flagella, where many pathological conditions are known. There also may be some changes in the tubulin cytoskeleton of malignant cells, although this study has so far produced contradictory findings.

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Post-Script and Outlook,ed proteins, comparable in this aspect to the histones, but have evidently undergone mutations since the origin of the first “prototubulin” molecule — perhaps a billion years ago — from which the various . and . tubulins diverged.

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Book 1984Latest edition the work on col­ chicine and other mitotic poisons, the literature on microtubules was, 8 years ago, already increasing at an impressive rate. However, this monograph, which, contrary to other works on microtubules, tried to cover the whole field of research, from the fundamentals of the tubulin mo