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Titlebook: Microfluidics and Multi Organs on Chip; P. V. Mohanan Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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书目名称Microfluidics and Multi Organs on Chip
编辑P. V. Mohanan
视频video
概述Highlights designing and fabrication of microfluidic chips and their biomedical applications.Present strategies for designing organ-on-a-chip and human-on-a-chip.Reviews microfluidic devices for drug
图书封面Titlebook: Microfluidics and Multi Organs on Chip;  P. V. Mohanan Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive license t
描述.This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices.  It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening.  Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation,ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners..
出版日期Book 2022
关键词Microfluidics; Organ-on-a-chip; Disease modeling; Drug discovery; Precision medicine
版次1
doihttps://doi.org/10.1007/978-981-19-1379-2
isbn_softcover978-981-19-1381-5
isbn_ebook978-981-19-1379-2
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
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Microfluidics in Chemical Biology,udy or manipulate biological or natural products. Chemical biology helps develop bioassays for the quantification of various compounds. The wisdom from chemistry is used to develop techniques to purify proteins and nucleic acids or use small molecules for multiple applications, such as sensing, drug
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Microfluidics in Drug Delivery,sadvantages which often nullify the therapeutic potential and render the drug ineffective. To circumvent some of these obstacles, microfluidics has emerged as a viable alternative over the past few decades, providing much-needed breakthroughs in the domain of nanotechnology to help formulate nanopar
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Background and Organ on a Chip,e difficulties to interconnect many organs together into an organ system. The motivation for interconnecting organ models is to better predict observations in vitro with the corresponding human reaction. Currently, experimental animals are used to get information on the organism levels. However, the
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Cells and Organs on a Chip in Biomedical Sciences,ical organ biomimetic systems built on microfluidic chips known as organ-on-chip (OOC). This integration of both electronic and fluidic components onto a single chip using a combination of bioengineering, cell biology and biomaterial technology has sparked research interest for newer applications in
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