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Titlebook: Microbial Infections; Role of Biological R Herman Friedman,Thomas W. Klein,Hideyo Yamaguchi Book 1992 The Editor(s) (if applicable) and The

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Identification and Characterization of Mammalian Cell Membrane Receptors for LPS-Endotoxin, non-self. To this end, the mammalian host has evolved multiple recognition systems by which non-self may be readily distinguished from self. Such discrimination systems exist at many levels, from the relatively simple, yet elegant, mechanisms for polysaccharide-dependent recognition of non-self by
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Bacterial Polysaccharides, Endotoxins, and Immunomodulation,ecause athymic nude mice and thymus-bearing mice, make antibody responses of the same magnitude (1–4). However, there is much evidence that the antibody response to SSS-III is indeed regulated in both a positive and a negative manner by two types of thymus-derived (T) lymphocytes with opposing funct
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Suppression of Antibody Forming Cells by Lipid a Analogs,re powerful adjuvants to the immune response when given with antigen (2) (or several days after antigen in the case of pneumococcal antigens [3]); (b) contrariwise when given 1–2 days before antigen a profound suppression of antibody ensues (4) and (c) 1–2 days after LPS a marked increase in resista
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BRM Activities of Low-Toxic , Lipopolysaccharides,r than the LD. of .-LPS(80 μg/mouse). Toxicity measured by decrease in body weight of BP-LPS-injected mice was similarly low. BP-LPS had strong antitumor activities against various murine syngeneic tumors, and its systemic administration caused clear regression of such as MM46 mammary carcinoma and
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Protective Effects of Cytokines in Murine Salmonell,almonella infects mice, the organisms multiply in the phagocytic cells, especially in the spleen and liver, and can kill the mice within a week. Phagocytic cells play an important role in the innate resistance of mice to infection by Salmonella. The outcome of an infection is influenced by a number
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