| 书目名称 | Microbial Gene Essentiality: Protocols and Bioinformatics |
| 编辑 | Andrei L. Osterman,Svetlana Y. Gerdes |
| 视频video | |
| 概述 | Offers a comprehensive, up-to-date collection of all the main strategies of experimental genome-scale gene essentiality analysis.Contains a detailed description of the procedures as well as a discussi |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | .Microbial Gene Essentiality: Protocols and Bioinformatics contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. In addition to wet-lab protocols, the book describes (i) statistical methods essential for planning successful large-scale essentiality screens, as well for data evaluation and analysis; (ii) in-silico prediction of gene essentiality using genome-scale reconstructed metabolic models; and (iii) data integration and comparative analysis in the context of genomic databases. This volume provides researchers with a first-stop guide for choosing the most appropriate strategy for planned essentiality studies. Experimental and computational aspects are equally important in genome-scale gene essentiality analysis, as in all other genomic technologies, and Microbial Gene Essentiality: Protocols and Bioinformatics reflects both of these aspects. All protocols follow the successful Methods in Molecular Biology™ series format, each offering an introduction outlining the principles behind the techniques, step-by-step instructions, lists |
| 出版日期 | Book 2008 |
| 关键词 | Bur; Escherichia coli; Genomic databases; In-silico prediction; Metabolic models; Microarray; Microbial ge |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-59745-321-9 |
| isbn_softcover | 978-1-61737-529-3 |
| isbn_ebook | 978-1-59745-321-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Humana Press 2008 |
发表于 2025-3-21 17:58:33
