| 书目名称 | MicroRNA Interference Technologies | | 编辑 | Zhiguo Wang | | 视频video | | | 概述 | Includes supplementary material: | | 图书封面 |  | | 描述 | .MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of around 22-nucleotides long, have rapidly emerged as one of the key governors of the gene expression regulatory program in cells of varying species, with ever-increasing implications in the control of the fundamental biological processes and in the pathogenesis of adult humans. The exciting findings in this field have inspired us with a premise and a promise that miRNAs will ultimately be taken to the heart for therapy of human disease. While miRNAs have been considered potential therapeutic targets for disease treatment, it remains obscured what strategies we can use to achieve the goal. In the past years, we have witnessed a rapid evolving of many creative, innovative, inventive strategies and methodologies pertinent to miRNA research and applications. These technologies have convincingly demonstrated their efficacy and reliability in producing gain-of-function or loss-of-function of miRNAs through targeting miRNA expression/biogenesis/function, providing new tools for elucidating miRNA functions and opening up a new avenue for the development of new agents targeting miRNAs for therapeutic aims. The present book provide | | 出版日期 | Book 2009 | | 关键词 | Activation; Nucleotide; gene expression; gene therapy; interference technology; miRNA; miRNAs | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-00489-6 | | isbn_softcover | 978-3-642-10151-9 | | isbn_ebook | 978-3-642-00489-6 | | copyright | Springer-Verlag Berlin Heidelberg 2009 |
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发表于 2025-3-21 20:01:34
