Titlebook: Methods of Mathematical Oncology; Fusion of Mathematic Takashi Suzuki,Clair Poignard,Vito Quaranta Conference proceedings 2021 Springer Nat

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Mathematical Modeling of Cancer Signaling Addressing Tumor Heterogeneitybutes to drug resistance and stemness, and the diversity of cancer subtypes contributes to different therapeutic efficacy between individuals. However, the whole mechanisms associated with heterogeneity in signal transduction are poorly understood. In this review, I introduce several mathematical mo

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The First Step Towards the Mathematical Understanding of the Role of Matrix Metalloproteinase-8 in C or assists the local growth of cancer. In addition, while other types of MMPs appear in either soluble or (cancer cell) membrane-bound form MMP-8 seems to appear in both. We take the first step in unravelling this dual nature of MMP-8 by shedding some mathematical light into its properties. To this

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Mathematical Modeling of the Dimerization of EGFR and ErbB3 in Lung Adenocarcinoma lung adenocarcinoma with . mutations. However, resistant tumors inevitably arise. One of the mechanisms conferring gefitinib resistance is the amplification of the . gene, which is observed in 5–22% of all cases. A previous study suggested that MET overexpression may cause gefitinib resistance thro

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Selective Regulation of the Insulin-Akt Pathway by Simultaneous Processing of Blood Insulin Pattern selective insulin responses .; however, the mechanisms by which different temporal patterns of insulin selectively regulate downstream molecules remain unknown. Revealing the mechanisms of selective regulation by temporal patterns of insulin is pivotal for understanding insulin actions ...We examin

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Time Changes in the VEGF-A Concentration Gradient Lead Neovasculature to Engage in Stair-Like Growthe development of these clinical entities are not fully understood. We previously reported a novel in vivo angiogenesis model as a useful disease model of arteriovenous malformation. With this model, the arterial graft was collected from the left carotid artery and sutured to the left jugular vein as

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Signaling Networks Involved in the Malignant Transformation of Breast Cancernt and have higher tumorigenicity than the surrounding breast cancer cells (non-CSCs). We aimed to elucidate the various signaling networks involved in the transformation of mammary epithelial cells into tumor cells based on literature review. We found that constitutive activation of the NF-. pathwa

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Hiroyuki Kubotauirements needed. This research discusses the conception, inception and implementation of the framework for mobile augmented reality tourism application. Thus, the objective of this study to analyze and construct requirements needed for a mobile augmented reality tourism application framework and to