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Titlebook: Methods Used in Adenosine Research; David M. Paton Book 1985 Springer Science+Business Media New York 1985 adenosine.blood.blood vessel.ca

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书目名称Methods Used in Adenosine Research
编辑David M. Paton
视频video
图书封面Titlebook: Methods Used in Adenosine Research;  David M. Paton Book 1985 Springer Science+Business Media New York 1985 adenosine.blood.blood vessel.ca
描述In their classic paper in 1929, Drury and Szent-Gyorgyi described a number of the important cardiovascular actions of adenosine. Another thirty years were to pass before the possible physiological role of adenosine in coronary vasodilation was studied by Berne and others. Since then, there has been a tremendous increase in research into the actions of adenosine. Workers from many disciplines have employed a wide variety of techniques, since adenosine is a product of and a substrate for a number of metabolic pathways, is transported into cells, and acts at discrete receptor sites to modulate the activity of adenylate cyclase and to produce important actions on many cells and tissues including platelets, adipo­ cytes, heart, blood vessels, and other smooth muscles. International symposia on the actions of adenosine were held in 1978, 1981, and 1982, and the proceedings of these symposia have been published (Baer and Drummond, 1979; Daly et at., 1983; Berne et at., 1983). Since it is not the primary purpose of the present volume to review our current understanding of the nu­ merous actions of adenosine, these volumes should be consulted for such details. Rather, the present volume has
出版日期Book 1985
关键词adenosine; blood; blood vessel; cardiovascular; cardiovascular actions; cells; heart; metabolism; muscle; pha
版次1
doihttps://doi.org/10.1007/978-1-4684-4886-3
isbn_softcover978-1-4684-4888-7
isbn_ebook978-1-4684-4886-3
copyrightSpringer Science+Business Media New York 1985
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Measurement and Inhibition of Membrane Transport of Adenosines, transport is a primary step both in the formation and in the disposition of extracellular adenosine. This chapter is concerned with the measurement of adenosine transport in cell suspensions and with the potent inhibition of this process by several agents. Because of the emphasis of this volume o
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The Classification of Receptors for Adenosine and Adenine Nucleotides an appraisal of the proposed A1/A2 subclassification of the Pi purinoceptor. A more detailed consideration of these individual aspects may be found in accompanying chapters. We conclude the chapter with a brief assessment of the validity of the existing classification systems and the prospects for
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The Pharmacologic Estimation of Potencies of Agonists and Antagonists in the Classification of Adenoerimental conditions) such that meaningful dependent variables can be obtained. Also, quantitative estimates of agonist efficacy, a quantity currently inaccessible in biochemical binding studies, can be obtained from experiments in isolated tissues. Thus, drug affinity and efficacy can be quantified
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ymposia have been published (Baer and Drummond, 1979; Daly et at., 1983; Berne et at., 1983). Since it is not the primary purpose of the present volume to review our current understanding of the nu­ merous actions of adenosine, these volumes should be consulted for such details. Rather, the present volume has978-1-4684-4888-7978-1-4684-4886-3
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Ulrich Schwabearchers that are interested in either the scientific or philosophical aspects of computational thinking, and can further the debate between the two approaches..978-3-030-86090-5978-3-030-86088-2Series ISSN 1860-949X Series E-ISSN 1860-9503
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Jeffrey S. Fedan,G. Kurt Hogaboom,John P. O’Donnell,David P. Westfallarchers that are interested in either the scientific or philosophical aspects of computational thinking, and can further the debate between the two approaches..978-3-030-86090-5978-3-030-86088-2Series ISSN 1860-949X Series E-ISSN 1860-9503
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