Titlebook: Metabolism and Functions of Bioactive Ether Lipids in the Brain; Akhlaq A. Farooqui,Tahira Farooqui,Lloyd A. Horroc Book 2008 Springer-Ver

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Metabolism and Functions of Bioactive Ether Lipids in the Brain978-0-387-77401-5

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Roles of Plasmalogens in Brain,onent of cellular membranes and a major reservoir for arachidonic and docosahexaenoic acids (AA and DHA), plasmalogens are also involved in transport of ions across plasma membranes (Gross, 1985), membrane fusion (Lohner, 1996), protection of cellular membranes against oxidative stress (Zoeller et a

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Involvement of Plasmalogens in Neurological Disorders,rmation, not only from the plasma membrane to the nucleus, but also from one cell to another through chemical mediators generated during the catabolism of various glycerophospholipids (Guan et al., 1999; Farooqui and Horrocks, 2007). Neural membranes are highly interactive and dynamic. These propert

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Degradation of Platelet-Activating Factor in Brain,lls in response to neurotransmitters (glutamate and its analogs), cytokines (tumor necrosis factor-α, interferon-γ, interleukin-1), and pathological situations (Sogos et al., 1990; Prescott et al., 2000; Karasawa et al., 2003; Kunievsky and Yavin, 1994). PAF is normally present in the mammalian tiss

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Roles of Platelet-Activating Factor in Brain,cytes, and microglia), platelets, leukocytes, monocytes, macrophages, endothelial cells, and smooth muscle cells (Aihara et al., 2000) (Montrucchio et al., 2000). A variety of stimuli, including those producing inflammation, promote the synthesis and release of PAF from neural and nonneural cells. A