书目名称 | Metabolic Aspects of Alcoholism | 编辑 | Charles S. Lieber (Chief, Professor of Medicine an | 视频video | | 图书封面 |  | 描述 | In the first annual report on Alcohol and. Health to Congress (December, 1971), the then HEW Secretary Elliot L. Richardson called alcohol ‘the most abused drug in the United States‘. The report revealed that nine million Americans are alcohol abusers and that alcoholic individuals represent almost 10 % of the nation‘s work force. With spreading alcoholism, the incidence of physical damage due to alcohol has greatly increased. A question which is often raised is ‘in which way does an alcoholic differ from a non-alcoholic?‘ Inquiries have focused on psychological make-up, behavioural differences and socioeconomic factors. More recently, however, physical differences have been delineated. Prior to the development of various disease entities, chronic ethanol exposure results in profound biochemical and morphological changes. Consequently an alcoholic does not respond normally to alcohol, or other drugs or even other toxic agents. Some of these persistent biochemical and morphological changes are the consequences of the injurious effects of ethanol, whereas others may represent the possible adaptive responses to the profound changes in intermediary metabolism which are a direct and im | 出版日期 | Book 1977 | 关键词 | alcohol; alcoholism; behavior; blood; bone; bone marrow; brain; drug; drugs; ethanol; health; heart; liver; metab | 版次 | 1 | doi | https://doi.org/10.1007/978-94-011-6153-4 | isbn_softcover | 978-94-011-6155-8 | isbn_ebook | 978-94-011-6153-4 | copyright | MTP Press Limited 1977 |
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