书目名称 | Meningococcal Disease | 编辑 | John M. Walker,Andrew J. Pollard,Martin C. J. Maid | 视频video | | 概述 | Includes supplementary material: | 丛书名称 | Methods in Molecular Medicine | 图书封面 |  | 描述 | Meningococcal septicemia and meningitis continue to be important causes of devastating illness, death, and long-term disability in both developed and resource-poor countries of the world. Few diseases have attracted as much public attention, or are as feared by parents and family members, as well as the medical staff who have to care for affected patients. The unexpected and unp- dictable occurrence of the disease in previously healthy children and young adults, its rapid progression, and the frequent occurrence of purpura fulminans with the resulting gangrene of limbs and digits and the requirement for mutilating s- gery, have all heightened both public and medical interest in the disease. Over the past two decades there has been a rapid increase in knowledge of many aspects of meningococcal disease as a result of intensive efforts by workers in many different fields: clinicians have studied the early presenting features and acute pathophysiology of the disorder; clinical scientists have explored the immunopathological mechanisms responsible for disease and have highlighted the important roles played by the host inflammatory response and pro-inflammatory cytokines in mediating dam | 出版日期 | Book 2001 | 关键词 | infectious diseases | 版次 | 1 | doi | https://doi.org/10.1385/1592591493 | isbn_softcover | 978-1-61737-221-6 | isbn_ebook | 978-1-59259-149-7Series ISSN 1543-1894 Series E-ISSN 1940-6037 | issn_series | 1543-1894 | copyright | Humana Press 2001 |
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