| 书目名称 | Membrane Protein Structure Determination | | 副标题 | Methods and Protocol | | 编辑 | Jean-Jacques Lacapère | | 视频video | | | 概述 | Addresses significant hurdles to membrane protein purification.Describes techniques that permit the capture of atomic scale pictures of membrane proteins.Includes tips for avoiding protocol pitfalls.I | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | Membrane proteins, representing nearly 40% of all proteins, are key components of cells involved in many cellular processes, yet only a small number of their structures have been determined. Membrane Protein Structure Determination: Methods and Protocols presents many detailed techniques for membrane protein structure determination used today by bringing together contributions from top experts in the field. Divided into five convenient sections, the book covers various strategies to purify membrane proteins, approaches to get three dimensional crystals and solve the structure by x-ray diffraction, possibilities to gain structural information for a membrane protein using electron microscopy observations, recent advances in nuclear magnetic resonance (NMR), and molecular modelling strategies that can be used either to get membrane protein structures or to move from atomic structure to a dynamic understanding of a molecular functioning mechanism. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, a | | 出版日期 | Book 2010 | | 关键词 | BCG; Electron microscopy; Membrane protein purification; Molecular modelling; Nuclear magnetic resonance | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-762-4 | | isbn_softcover | 978-1-4939-6117-7 | | isbn_ebook | 978-1-60761-762-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC 2010 |
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发表于 2025-3-21 19:25:06
