书目名称 | Melatonin, Neuroprotective Agents and Antidepressant Therapy | 编辑 | Francisco López-Muñoz,Venkataramanujam Srinivasan, | 视频video | | 概述 | Detailed information on etiology of mood disorders.Provides recent thoughts on melatonin, its receptors and their role in circadian rhythms, and sleep and mood disorders.Describes therapeutic actions | 图书封面 |  | 描述 | This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms, abnormalities in monoaminergic neurotransmitter mechanisms, glutamatergic release mechanisms, hippocampal neurogenesis, and abnormal immune and cytokine release mechanisms. Many antidepressants that are in clinical use today including the recently introduced novel agentslike agomelatine or other antidepressants cause clinical remission by resynchronizing disrupted circadian rhythms and melatonin receptor functions, enhancing monoaminergic neurotransmission, promoting hippocampal neurogenesis, | 出版日期 | Book 2016 | 关键词 | Agomelatine; Chronobiology of mood disorders; Hippocampal neurogenesis, depression and antidepressants | 版次 | 1 | doi | https://doi.org/10.1007/978-81-322-2803-5 | isbn_softcover | 978-81-322-3842-3 | isbn_ebook | 978-81-322-2803-5 | copyright | Springer India 2016 |
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