Titlebook: Mechanotransduction of the Hair Cell; Wei Xiong,Zhigang Xu Book 2018 The Author(s) 2018 Hair cell.Mechanotransduction.Cochlea.Stereocilia.

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书目名称Mechanotransduction of the Hair Cell影响因子(影响力)




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Biophysical Properties of Mechanotransduction,hange of hair cells (Hudspeth and Corey, Proc Natl Acad Sci USA 74(6):2407–2411, 1977). Nevertheless, whole-cell patch clamp was applied to hair cells to achieve a detailed information of the MET channel including some single-channel behaviour (Ohmori, J Physiol 359:189–217, 1985). From then on, res

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2211-9353 mechanotransduction, including cellular structure, biophysic.This book summarizes the emerging experimental evidence on hair-cell mechanotransduction, and covers hair’s cellular structure, biophysical properties, molecular components and functions. Auditory hair cells convert sound-induced vibration

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lipids

Book 2018te. Recent advances in molecular genetics and biophysics have helped us gain deeper insights into this process, especially the molecular constituent and operation of the channel complex. This book provides a cutting-edge snapshot for all readers who are interested in or studying how auditory hair cells detect sound. .

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aggravate

敬礼

Cellular Structure for Hair-Cell Mechanotransduction,e deflected positively, tension of tip links increases, which changes the conformation of MET channels and increases their open probability. Driven by the potential difference and ion concentration difference, cations flux into hair cells through the MET channels and cause membrane depolarization.

synchronous

Molecular Components of Mechanotransduction Machinery,gral components of the machinery, but confirmative evidences for them as the pore-forming subunits of the channel are still missing. Lastly, we will briefly discuss the recent identification of PIEZO2 as the channel responsible for the reverse-polarity MET currents.

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