Titlebook: Mechanosensing Biology; Masaki Noda (Professor, Director) Book 2011 Springer 2011

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Molecular Mechanisms Underlying Mechanosensing in Vascular Biology stress and transmit signals to the interior of the cell, leading to cell responses that involve changes in cell morphology, cell function, and gene expression. These EC responses to shear stress are thought to play important roles in blood-flow-dependent phenomena, such as vascular tone control, an

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Mechanobiology During Vertebrate Organ Developmentidermal region during vertebrate embryogenesis, and is regulated at the gene level by appropriate concentrations of cell signaling proteins such as bone morphogenetic protein (BMP), fibroblast growth factor (FGF), and Wnt (reviewed by Meulemans and Bronner-Fraser 2004). Many genes participate in thi

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Mechanobiology in Skeletal Muscle: Conversion of Mechanical Information into Molecular Signalange in gene expression, fiber-type transition, satellite cell activation, and angiogenesis (Bassel- Duby and Olson 2006; Blaauw et al. 2009). Interestingly, at the early phase of muscle hypertrophy, protein synthesis significantly increases (Baar et al. 2006), and later the transcription of growth-

RAGE

overrule

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形上升才刺激

collagenase

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characteristic